Gamecock Club Lacrosse aimed for a remarkable "three-peat" in the Men's Collegiate Lacrosse Association for the 2022-23 season. Despite their valiant effort and several closely contested matches, the Gamecocks concluded the season with a record of 8 – 10. One notable highlight of their season was the team's journey to California during Spring Break, where they faced formidable opponents such as Chapman University, University of Concordia, and California Polytechnic State University.